Isotopically Labeled Compounds
Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphorylcholine-d79 | 326495-39-0 | 99.3% | 869.63 g/mol | C44H9D79NO8P | 1 MG
Deuterated form of 1,2-distearoyl-sn-glycero-3-phosphorylcholine used as a saturated phospholipid for liposome and lipid nanoparticle formulations. Deuteration replaces hydrogen atoms with deuterium to enable analytical tracing and may affect metabolic stability.
- Deuterium-labeled phospholipid for tracing and mass-shift studies.
- High purity suitable for formulation and analytical work.
- Small pack sizes for research-scale experiments.
- Compatible with liposome and lipid nanoparticle synthesis protocols.
Medchemexpress LLC Sucrose-d14 (D-(+)-Saccharose-d14) | 57-50-1 | 99.0% | 1 MG
Sucrose-d14 is the deuterium labeled Sucrose, a disaccharide composed of two monosaccharides, glucose and fructose. It can be applied in animal models for metabolic disease, obesity, and diet preference. This product serves as a valuable tool for quantitative analysis in various research applications.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium substitution can affect the pharmacokinetic and metabolic profiles of drugs.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process.
Medchemexpress LLC Naringenin-d4 | 1192260-78-8 | MFCD34676368 | 99.9% | 276.28 | C15H8D4O5 | 10 MG
Naringenin-d4 is the deuterated (stable isotope-labelled) analogue of the flavanone naringenin, supplied as a solid reference standard for analytical, tracer, and metabolic studies. It is commonly used as an internal standard in mass spectrometry and for pharmacokinetic or mechanistic investigations.
- Deuterium-labelled analogue suitable as an internal standard for LC-MS/MS.
- High chemical purity for reliable quantitative analysis.
- Supplied as a dry powder for convenient handling and storage.
- Available in small package sizes, including 10 mg, for analytical workflows.
- Structural identifiers provided for cheminformatics and method development.
- Stable when stored under recommended conditions for long-term use.
Medchemexpress LLC Clomipramine-d3 hydrochloride | 1398065-86-5 | 100.0% | 10 MG
Clomipramine-d3 hydrochloride is the deuterium-labeled hydrochloride salt of clomipramine supplied as a high-purity solid for use as an analytical standard and stable-isotope tracer in research applications such as mass spectrometry, pharmacokinetics, and isotope-dilution assays.
- Deuterated internal standard for mass spectrometry and isotope-dilution workflows.
- Hydrochloride salt form supplied as a solid, white to off-white.
- High purity suitable for analytical applications (99.98% reported).
- Molecular weight 354.33; formula C19H21D3Cl2N2.
- Packaged as 10 MG; store at -20°C, sealed, protect from moisture.
Medchemexpress LLC 1-Adamantan-d15-amine | 33830-10-3 | MFCD01317436 | 98.0% | 166.34 | C10H2D15N | 10 MG
Amantadine-d15 (1-Adamantanamine-d15) is the deuterium-labeled isotopologue of amantadine supplied as a solid analytical standard for use in mass spectrometry, isotope-dilution quantitation, metabolic, and pharmacokinetic studies. The product is characterized by its molecular formula and verified purity on the certificate of analysis, and is intended for use as an internal standard or tracer in quantitative workflows.
- High isotopic labeling suitable for mass spectrometry applications.
- Purity 98.0% as reported on the certificate of analysis.
- White to off-white solid for convenient storage and handling.
- Appropriate as an internal standard for LC-MS/MS and GC-MS quantitation.
- Provided in a 10 mg quantity for analytical use.
Medchemexpress LLC Sitagliptin-d4 hydrochloride | 486460-32-6 | 99.2% | 447.80 | 1 MG
Sitagliptin-d4 hydrochloride is the deuterium labeled Sitagliptin hydrochloride. This compound is an orally active and highly selective DPP4 inhibitor with an IC50 value of 19 nM. It blocks the degradation of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) by competing inhibition (Kᵢ = 1 nM), thereby increasing active incretin levels. It can also directly stimulate GLP-1 secretion by intestinal L cells, independent of DPP-4, by activating cAMP/PKA and ERK1/2 pathways. Sitagliptin hydrochloride shows protective effects on pancreatic islet grafts in type 1 diabetes models and can be used for studying type 1 and type 2 diabetes.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Abcam C6-NBD-ceramide, fluorescent sphingosine analog, 100UG
MW 575.7 Da, Purity >98%. Fluorescent C6:0-sphingosine analog. For use in CERT trafficking studies and as internal standard. Possible activity in vitro. See similar compounds
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC L-Ascorbic acid-13C-2 | 1313730-17-4 | 95.0% | 5 MG
L-Ascorbic acid-13C-2 is the 13C labeled L-Ascorbic acid, an electron donor and endogenous antioxidant agent. It inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM and is also a collagen. This compound is useful in various analytical applications.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Anastrozole-d12 | 120512-32-5 | 99.7% | C17H7D12N5 | 1 MG
Anastrozole-d12 is the deuterium labeled Anastrozole, a potent and highly selective aromatase inhibitor. It inhibits human placental aromatase with an IC50 of 15 nM. This compound is intended for research use only and can serve as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuterium substitution may impact the pharmacokinetic and metabolic profiles of drugs. It appears as a white to off-white solid.
- Potent and highly selective aromatase inhibitor
- Inhibits human placental aromatase with an IC50 of 15 nM
- Deuterium labeled Anastrozole
- Can be used as a tracer for quantitative analysis
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- White to off-white solid appearance
- Deuterium substitution can affect pharmacokinetic and metabolic profiles
Medchemexpress LLC Sotalol-d6 hydrochloride | 1246820-85-8 | 98.0% | 314.86 | C12H15D6ClN2O3S | 10 MG
Sotalol-d6 hydrochloride is the deuterium-labeled isotopologue of sotalol hydrochloride provided as the hydrochloride salt for use as a stable-isotope reference standard in analytical and pharmacokinetic research. The deuterated compound is intended for tracer, quantitation, and internal standard applications in LC-MS workflows.
- Deuterium-labeled internal standard for LC-MS quantitation.
- Hydrochloride salt form for stability and solubility.
- High purity (≈98.0%) suitable for analytical use.
- Suitable for pharmacokinetic and tracer studies.
- Available in small reference pack sizes (for example, 10 mg).
Medchemexpress LLC D-(+)-glucose-d12-1 | 89798-27-6 | 99.4% | 192.23 g/mol | C6D12O6 | 10 MG
D-Glucose-d12-1 is a deuterium-labeled form of D-glucose (C6D12O6) intended for use as an isotopic tracer and as a quantitative internal standard in analytical methods. It is supplied as a high-purity crystalline powder for laboratory research and analytical workflows.
- Uniformly deuterated glucose (C6D12O6).
- High purity: 99.4%.
- Used as tracer and internal standard for NMR, GC-MS, and LC-MS.
- Supplied as a stable crystalline powder suitable for analytical preparation.
- Recommended storage: powder at -20°C for long-term stability.
Medchemexpress LLC Amantadine-d6 | 1219805-53-4 | MFCD19704894 | 98.1% | 157.29 | C10H11D6N | 10 MG
Amantadine-d6 is a deuterium-labeled analogue of amantadine supplied as a stable isotope standard for research and analytical applications, including mass spectrometry, metabolic, and pharmacokinetic studies.
- Deuterium-labeled (d6) amantadine for stable isotope applications.
- High chemical and isotopic purity (98.1%).
- Molecular formula C10H11D6N; molecular weight 157.29.
- Suitable as an internal standard for LC-MS/MS and other analytical methods.
- Available in small-mass packaging for analytical workflows (e.g., 10 MG).
Cambridge Isotope Laboratories L-TRYPTOPHAN (15N2, 98%), 0.5 G, 204634-20-8
L-TRYPTOPHAN (15N2, 98%), 0.5 G, 204634-20-8
Cambridge Isotope Laboratories AMMONIUM NITRATE (15N2, 98%+), 1 G, 43086-60-8
AMMONIUM NITRATE (15N2, 98%+), 1 G, 43086-60-8